BIOMEDICAL RESEARCH DEPARTMENT

 BIOTECHNOLOGY
RESEARCH INSTITUTE

BIOMEDICAL
RESEARCH DEPARTMENT

The
Biomedical Research Department has
three sections 

·        
BRI-BMB-1:-Medicines
and drug research 

·        
BRI-BMB-2:-
Molecular
biology

·        
BRI-BMB-3:-Disease
diagnostics and aging research

 Table.  Status of Research projects in the Biomedical
Research departments of BRI



Department


On-going


Suspended


Completed


Total


Remark


Biomedical
Research


7


2


4


13


 

 Table. Publication status of the research
projects in the Biomedical Research departments



Department


Ready


Submitted


Published


Remark


Biomedical
Research department


5


2


4


 

 

 

 List of published article

1.      Zewdie Mekonnen
Nigussie, Menyechil Yenealem Antigegn, Seleshi Andualem Mekuriaw, Endalkachew
Nibret Semegn
(2015).  Androgenic steroid composition of the hexane/methanol whole plant extract
of Solanecio tuberosus (Selbilla) around Lake Tana Northwest Ethiopia.
 Journal of Medicinal Herbs and Ethnomedicine

2.     
Asmare` Amuamuta, Zewdie Mekonnen and
Agmassie Agazie (
2014).
Extraction and Analysis of Oil/Fat and Fatty Acids
Content from Different Indigenous Fish of Lake Tana Source, Northwest Ethiopia,
World Journal of Fish and Marine Sciences 6 (5): 417-423

3.     
Asmare`
Amuamuta, Zewdie Mekonnen and Endalew Gebeyehu

(2015). Traditional therapeutic uses and phytochemical screening of some selected
indigenous medicinal plants from Northwest Ethiopia. African Journal of Pharmacology and Therapeutics Vol. 4 No. 3 Pages
80-85

4.     
Martha
Tibebu Lemma, Yohannes Zenebe, Begna Tulu,Daniel Mekonnen, Zewdie Mekonnen

(2015). Methicillin Resistant Staphylococcus aureus among HIV Infected
Pediatric Patients in Northwest Ethiopia: Carriage Rates and Antibiotic
Co-Resistance Profiles .PLOS  ONE

 Table: Biomedical Research Department staff



No.


Name of the researcher


Field of specialization


Academic Rank


Position


E-mail addresses


Mobile no.


1.       


Zewdie Mekonnen


Medical
Biochemistry


Lecturer


Biomedical Research Department head


Zewdmek28@yahoo.com


0911073157


2.       


Yohannes Zenebe


infectious
and tropical Disease


lecturer


Disease
diagnostics and aging research section -head


yohabt22@gmail.com


0918704688


3.       


Dr Abaineh Munisha


Biomedical
science


Ass.
Professor


Molecular
biology section head


abitew2003@yahoo.com


0918705769


4.       


Yesuf Adem


Medical
Microbiology


lecturer


Disease diagnostics and aging
research section -head


yesufadems@yahoo.com


0912157552

 

Table: Biomedical Research Department researcher



No.


Name of the researcher


Field of specialization


Academic Rank


E-mail addresses


Mobile no.


1.       


Zewdie Mekonnen


Medical
Biochemistry


Lecturer


Zewdmek28@yahoo.com


0911073157


2.       


Daniel Mekonnen


Medical
microbiology


Lecturer


nigusdaniel@gmail.com


0912990288


3.       


Begna Tulu


Medical
microbiology


Ass.
Professor


tulubegana@yahoo.com


0911943377


4.       


Dr Abaineh Munisha


Biomedical
science


Ass.
Professor


abitew2003@yahoo.com


0918705769


5.       


Mulate Yimer


Medical
Parasilogist


Assistant
Profesor


yimermulat@gmail.com


0943390361


6.       


Wondemagegn Mulu


Medical
Microbiology


Assistant
profesor


wenedem_32@yahoo.com


0918706921


7.       


Yesuf Adem


Medical
Microbiology


lecturer


yesufadems@yahoo.com


0912157552


8.       


Dr Bezuayehu Kerisew


Molcular
Biology


Assistant  profesor 


bizushk@yahoo.com


0918760090


9.       


Dr  endalekachew  Niberet


Biomedical  Science


Assistant  profesor 


endtg2002@yahoo.com


0918309704


10.   


Yohannes Zenebe


infectious
and tropical Disease


lecturer


yohabt22@gmail.com


0918704688


11.   


Yohannes Abere


Medical
Biochemistry


lecturer


abere_yohannes@yahoo.com


0910511160


12.   


Awoke  Derbie


Medical
Microbiology


Lecturer


Awe.love2000@gmail.com


0913059887

Table. List of research projects under biomedical
Research department and their status



Thematic
area


         Code


Research
title


Investigators


Status
(%)


 

 

 

 

 

 

 

 

 

Medicines
and drug research (BRI-BMB-1)


BRI-BMB-1001


Identification
of steroids from Solanecio tuberosus extract(2005)


Zewdie M.,Seleshi A,Menyechile Y,Endalkachew N


Completed

·        
Community service has been
delivered


 

BRI-BMB-1002


Prevalence of Extended spectrum
beta-lactamases (ESBL) in Enterobacteriacaea from Clinical and environmental
(food and Water) isolates in Bahir Dar town, Ethiopia. 


Bayeh A.,Mulugeta K.  ,Wondemagne M.  


Ongoing (90 % )

-       Budget
for this year  taken


BRI-BMB-1003


Phytochemical and pharmacological study
on selectedindeginous medicinal plants

fromZegie and areas of Lake Tana
Monastries, Northwest Ethiopia


Dr. Asmare` A.,  Zewdie M., yohannes A


Completed

-       In-vivo
experiments completed  Going as planned


BRI-BMB-1004


Analysis of
Omega 3 fatty acid content from different indigenous fish of Lake Tana origin


Asmare A.,Zewdie M,Agmassie A


Completed



BRI-BMB-1005



Genetic Diversity,
Population Structure and factors for colonization by MRSA of HIV positive
paediatric patients in Northwest Ethiopia


Martha T, Yohannes Z., Zewdie M.

Daneil M.,  Began T


Completed

-       Manuscript
under preparation for publication

-       Going as planned


BRI-BMB-1006


Extensively Drug Resistant Tuberculosis and its associated factors in Amhara
National Regional State, Ethiopia: By MTBDRsl molecular line probe assay.


Daniel M.Aschalew A.
,Wondemagegn M. ,Baye A.,Yohannes Z.,Belaynew W.


-       Suspended
(the investigator taken budget for two projects before this)

-       With possible reinitiation


 

 

Molecular
biology (BRI-BMB-2)


BRI-BMB-2001


Detection of molecular markers related
to resistance to artemisinins in Plasmodium falciparum among health centers
in Bahir Dar Zuria district North West Ethiopia


Mulat Y. ,Bayeh A. ,Wondimagegn M.,
Arancha  A.


-       100%
completed

-       Manuscript
under preparation for publication

-       Going as planned


BRI-BMB-2002


Molecular epidemiology of Entamoeba
histolytica/ dispar infections and isolation of other pathogenic bacterial
infections among health centers in Gozamin district, east Gojjam zone.


Mulat Y. , Yohannes Z. , Bayeh
A.,Wondimagegn M., Jose M.


-       100%
completed

-       Manuscript
under preparation

-       Going as planned


 

 

 

 

 

 

 

 

Disease
diagnostics and aging research(BRI-BMB-3)


BRI-BMB-3001


Host Genetic Factors that Influence
Susceptibility to HIV infection and disease course among HIV/AIDS patients
visiting Felege Hiwot Hospital


Abaineh M.,Endalkachew N., Bizuayehu K.


Ongoing 
(50 % )

-       Chemicals
purchased and ordered

-       Sample
collected

-       Going as planned


 

BRI-BMB-3002


Population based reference intervals for
common haematological, immunological and

biochemical parameters in Amahara
Region, North West Ethiopia


Zewdie M.,Wondemagegn M., Asmare
A.,Bayeh A., Yohanese Z., Mulat Y.,Yesuf A., Martha T.


Completed for the two worda   (100 % )

-       Manuscript
for the two worda is under preparation for publication

-       Going as planned


BRI-BMB-3003


Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus
among patients   with Skin and Soft
Tissue Infections and on bed bug isolated from their residential  institutions  in Amhara National
Regional State, Ethiopia.


Daniel M., Yohannes Z.,Wondemagegn M. Baye A.,Martha
T. Lemma,D. Hailu C.


-       On-going

-       Reagents
purchased

-       Data
collection under way

-        Going
as planned


BRI-BMB-3004


Prevalence and Risk Factors of Latent
Tuberculosis Infection among High risk groups in Amhara National Regional
State, Ethiopia: A Cross-Sectional Study design by interferon gamma release
assay.


Begna T.,Daniel M.,Adane M. , Abebaw
K.,Martha T.


-       Suspended
due to huge budget demand

-       Submitted
for other grant under the institute

-       Suspended



BRI-BMB-3005



HIV/TB lymphadenitis
co-infection among TB lymphadenitis suspected patients and drug resistant
profile of TB isolates by GenoType MTBDRPlus molecular line probe assay in
North west  Ethiopia.


Yohannes Z., Begna
T.Wondemagegn M., Daniel M., Baye A.


On-going (10%)

-       Reagents
purchased

-       Data
collection under way

-       Going as planned

Seminars

1.     
“Structure and Function of Serum Amyloid A
Proteins” Dr Mehabaw Getahun Derebe is a Scientist, in Janssen Pharmaceuticals,
Spring House PA, USA፣from the University of Texas Southwestern Medical Center,
Dallas.

2.     
“Methicillin Resistant Staphylococcus
aureus and its associated factors among HIV positive Paedatric Patients in
Amhara National Regional State, Ethiopia: A cross Sectional Study Design”

3.     
Detection of molecular markers related to
resistance to artemisinins in Plasmodium falciparum among health centers in
Bahir Dar Zuria district North West Ethiopia  

4.     
Molecular epidemiology of Entamoeba
histolytica/ dispar infections and isolation of other pathogenic bacterial
infections among health centers in Gozamin district, east Gojjam zone

5.     
Phytochemical and pharmacological study on
selectedindeginous medicinal plants fromZegie and areas of Lake Tana
Monastries, Northwest Ethiopia 

6.     
Analysis of Omega 3 fatty acid content
from different indigenous fish of Lake Tana origin